Catalyst-free synthesis of 2-aryl-1,2-dihydro-quinazolin-4(1H)-thiones from 2-aminobenzothio-amides and aldehydes in water.

نویسندگان

  • Stefan Oschatz
  • Tom Brunzel
  • Xiao-Feng Wu
  • Peter Langer
چکیده

2-Dihydroquinazolin-4(1H)-thiones were prepared in up to excellent yields from 2-aminobenzothioamides and aldehydes. The reaction is carried out in water without the use of any catalyst or promoter. The sulfur-containing substrate can be obtained easily by thiation of the corresponding nitrile by solid sodium hydrosulfide.

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عنوان ژورنال:
  • Organic & biomolecular chemistry

دوره 13 4  شماره 

صفحات  -

تاریخ انتشار 2015